IgG2a monoclonal antibodies inhibit human tumor growth through interaction with effector cells.
Monoclonal antibodies of IgG2a isotype specifically inhibited growth of human tumors in nude mice. Twenty-three monoclonal antibodies of other isotypes showed no tumoricidal reactivity. Complement depletion of nude mice had no effect on tumor suppression by monoclonal antibody. The role of T and kil...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1982
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346757/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6289317/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.15.4761 |
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