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IgG2a monoclonal antibodies inhibit human tumor growth through interaction with effector cells.

Monoclonal antibodies of IgG2a isotype specifically inhibited growth of human tumors in nude mice. Twenty-three monoclonal antibodies of other isotypes showed no tumoricidal reactivity. Complement depletion of nude mice had no effect on tumor suppression by monoclonal antibody. The role of T and kil...

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Detalhes bibliográficos
Main Authors: Herlyn, D, Koprowski, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC346757/
https://ncbi.nlm.nih.gov/pubmed/6289317
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