Associations of serum sex steroid hormones and 5α-androstane-3α,17β-diol glucuronide concentrations with prostate cancer risk among men treated with finasteride

BACKGROUND: Finasteride, an inhibitor of 5 α-reductase (Type II), lowers intraprostatic dihydrotestosterone (DHT), which is reflected in serum as reduced 5α-androstane-3α,17β-diol glucuronide (3α-dG). It also modestly increases serum testosterone (T), estrone (E1) and estradiol (E2). In this altered...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kristal, Alan R., Till, Cathee, Tangen, Catherine M., Goodman, Phyllis J., Neuhouser, Marian L., Stanczyk, Frank Z., Chu, Lisa W., Patel, Sherfaraz K., Thompson, Ian, Reichardt, Juergen K., Hoque, Ashraful, Platz, Elizabeth A., Figg, William D., Van Bokhoven, Adrie, Lippman, Scott M., Hsing, Ann W
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467348/
https://ncbi.nlm.nih.gov/pubmed/22879203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-12-0695
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