Associations of serum sex steroid hormones and 5α-androstane-3α,17β-diol glucuronide concentrations with prostate cancer risk among men treated with finasteride

BACKGROUND: Finasteride, an inhibitor of 5 α-reductase (Type II), lowers intraprostatic dihydrotestosterone (DHT), which is reflected in serum as reduced 5α-androstane-3α,17β-diol glucuronide (3α-dG). It also modestly increases serum testosterone (T), estrone (E1) and estradiol (E2). In this altered...

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書誌詳細
主要な著者: Kristal, Alan R., Till, Cathee, Tangen, Catherine M., Goodman, Phyllis J., Neuhouser, Marian L., Stanczyk, Frank Z., Chu, Lisa W., Patel, Sherfaraz K., Thompson, Ian, Reichardt, Juergen K., Hoque, Ashraful, Platz, Elizabeth A., Figg, William D., Van Bokhoven, Adrie, Lippman, Scott M., Hsing, Ann W
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467348/
https://ncbi.nlm.nih.gov/pubmed/22879203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-12-0695
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