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ILK: a pseudokinase in the center stage of cell-matrix adhesion and signaling

Integrin-linked kinase (ILK) is a widely expressed and evolutionally conserved component of cell-extracellular matrix (ECM) adhesions. Although initially named as a kinase, ILK contains an unusual pseudoactive site that is incapable of catalyzing phosphorylation. Instead, ILK acts as a central compo...

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Detalhes bibliográficos
Main Authors: Qin, Jun, Wu, Chuanyue
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467332/
https://ncbi.nlm.nih.gov/pubmed/22763012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2012.06.003
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