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Increased Synapse Formation Obtained by T Cell Epitopes Containing a CxxC Motif in Flanking Residues Convert CD4+ T Cells into Cytolytic Effectors

The nature of MHC class II-binding epitopes not only determines the specificity of T cell responses, but may also alter effector cell functions. Cytolytic CD4+ T cells have been observed primarily in anti-viral responses, but very little is known about the conditions under which they can be elicited...

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Detalhes bibliográficos
Main Authors: Carlier, Vincent A., VanderElst, Luc, Janssens, Wim, Jacquemin, Marc G., Saint-Remy, Jean-Marie R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467281/
https://ncbi.nlm.nih.gov/pubmed/23056200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045366
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