CONSTITUTIVE ACTIVATION OF THE mTOR SIGNALING PATHWAY WITHIN THE NORMAL GLOMERULUS

Agents that target the activity of the mammalian target of rapamycin (mTOR) kinase in humans are associated with proteinuria. However, the mechanisms underlying mTOR activity and signaling within the kidney are poorly understood. In this study, we developed a sensitive immunofluorescence technique f...

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Detalhes bibliográficos
Main Authors: McMahon, Gearoid, Datta, Dipak, Bruneau, Sarah, Kann, Martin, Khalid, Myda, Ho, Jacqueline, Seto, Tatsuichiro, Kreidberg, Jordan A., Stillman, Isaac E., Briscoe, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467200/
https://ncbi.nlm.nih.gov/pubmed/22828505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.07.075
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