The solution structure of double helical arabino nucleic acids (ANA and 2′F-ANA): effect of arabinoses in duplex-hairpin interconversion

We report here the first structure of double helical arabino nucleic acid (ANA), the C2′-stereoisomer of RNA, and the 2′-fluoro-ANA analogue (2′F-ANA). A chimeric dodecamer based on the Dickerson sequence, containing a contiguous central segment of arabino nucleotides, flanked by two 2′-deoxy-2′F-AN...

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Detalhes bibliográficos
Main Authors: Martín-Pintado, Nerea, Yahyaee-Anzahaee, Maryam, Campos-Olivas, Ramón, Noronha, Anne M., Wilds, Christopher J., Damha, Masad J., González, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467067/
https://ncbi.nlm.nih.gov/pubmed/22798499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks672
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