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A Hedgehog Survival Pathway in ‘Undead’ Lipotoxic Hepatocytes

BACKGROUND & AIMS: Ballooned hepatocytes in nonalcoholic steatohepatitis (NASH) generate sonic hedgehog (SHH). This observation is consistent with a cellular phenotype in which the cell death program has been initiated but cannot be executed. Our aim was to determine if ballooned hepatocytes hav...

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書誌詳細
主要な著者: Kakisaka, Keisuke, Cazanave, Sophie C., Werneburg, Nathan W., Razumilava, Nataliya, Mertens, Joachim C., Bronk, Steve F., Gores, Gregory J.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467008/
https://ncbi.nlm.nih.gov/pubmed/22641094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2012.05.011
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