Effects of adrenal cortical steroids and osmotic blood-brain barrier opening on methotrexate delivery to gliomas in the rodent: the factor of the blood-brain barrier.

The effect of adrenal cortical steroids and osmotic blood-brain barrier modification on methotrexate delivery to normal and glioma-bearing rats was studied. In animals with the avian sarcoma virus-induced glioma, osmotic blood-brain barrier modification resulted in significantly increased delivery o...

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Bibliografiske detaljer
Main Authors: Neuwelt, E A, Barnett, P A, Bigner, D D, Frenkel, E P
Format: Artigo
Sprog:Inglês
Udgivet: 1982
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC346683/
https://ncbi.nlm.nih.gov/pubmed/6289301
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