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Effect of circadian clock mutations on DNA damage response in mammalian cells

The circadian clock is a global regulatory mechanism that confers daily rhythmicity on many biochemical and physiological functions, including DNA excision repair in mammalian organisms. Here, we investigated the effect of the circadian clock on the major DNA damage response pathways by using mouse...

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Main Authors: Gaddameedhi, Shobhan, Reardon, Joyce T., Ye, Rui, Ozturk, Nuri, Sancar, Aziz
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466558/
https://ncbi.nlm.nih.gov/pubmed/22918252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21771
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