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Spartan/C1orf124 is important to prevent UV-induced mutagenesis

Uninterrupted replication across damaged DNA is critical to prevent replication fork collapse and resulting double-strand DNA breaks. Rad18-mediated PCNA ubiquitination is a crucial event that triggers a number of downstream pathways important for lesion bypass. Here, we report characterization of S...

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Detalhes bibliográficos
Main Authors: Machida, Yuka, Kim, Myoung Shin, Machida, Yuichi J.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466550/
https://ncbi.nlm.nih.gov/pubmed/22894931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21694
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