Mucin Gene Deficiency in Mice Impairs Host Resistance to an Enteric Parasitic Infection

BACKGROUND & AIMS: Hyperplasia of mucin-secreting intestinal goblet cells accompanies a number of enteric infections, including infections by nematode parasites. Nevertheless, the precise role of mucins in host defense in nematode infection is not known. We investigated the role of the mucin (Mu...

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Bibliographic Details
Main Authors: Hasnain, Sumaira Z., Wang, Huaqing, Ghia, Jean–Eric, Haq, Nihal, Deng, Yikang, Velcich, Anna, Grencis, Richard K., Thornton, David J., Khan, Waliul I.
Format: Artigo
Language:Inglês
Published: W.B. Saunders 2010
Subjects:
Basic—Alimentary Tract
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466424/
https://ncbi.nlm.nih.gov/pubmed/20138044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.01.045
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