CD4(+) T cell‐mediated immunological control of enterochromaffin cell hyperplasia and 5‐hydroxytryptamine production in enteric infection

BACKGROUND: Enterochromaffin (EC) cells are dispersed throughout the gastrointestinal (GI) mucosa and are the main source of 5‐hydroxytryptamine (5‐HT) in the gut. 5‐HT has been implicated in the pathophysiology of several GI disorders, but the mechanisms regulating 5‐HT production in the gut are un...

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Detalhes bibliográficos
Main Authors: Wang, Huaqing, Steeds, Justin, Motomura, Yasuaki, Deng, Yikang, Verma‐Gandhu, Monica, El‐Sharkawy, Rami T, McLaughlin, John T, Grencis, Richard K, Khan, Waliul I
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994360/
https://ncbi.nlm.nih.gov/pubmed/17303597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2006.103226
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