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Mechanisms Underlying Food-Drug Interactions: Inhibition of Intestinal Metabolism and Transport

Food-drug interaction studies are critical to evaluate appropriate dosing, timing, and formulation of new drug candidates. These interactions often reflect prandial-associated changes in the extent and/or rate of systemic drug exposure. Physiologic and physicochemical mechanisms underlying food effe...

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Detalhes bibliográficos
Main Authors: Won, Christina S., Oberlies, Nicholas H., Paine, Mary F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466398/
https://ncbi.nlm.nih.gov/pubmed/22884524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2012.08.001
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