Expression and Function of PML-RARA in the Hematopoietic Progenitor Cells of Ctsg-PML-RARA Mice

Because PML-RARA-induced acute promyelocytic leukemia (APL) is a morphologically differentiated leukemia, many groups have speculated about whether its leukemic cell of origin is a committed myeloid precursor (e.g. a promyelocyte) versus an hematopoietic stem/progenitor cell (HSPC). We originally ta...

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Détails bibliographiques
Auteurs principaux: Wartman, Lukas D., Welch, John S., Uy, Geoffrey L., Klco, Jeffery M., Lamprecht, Tamara, Varghese, Nobish, Nagarajan, Rakesh, Ley, Timothy J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466302/
https://ncbi.nlm.nih.gov/pubmed/23056333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046529
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