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Inhibition of OCTN2-Mediated Transport of Carnitine by Etoposide
OCTN2 is a bifunctional transporter that reabsorbs filtered carnitine in a sodium dependent manner and secretes organic cations into urine as a proton antiport mechanism. We hypothesized that inhibition of OCTN2 by anticancer drugs can influence carnitine resorption. OCTN2-mediated transport inhibit...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3466062/ https://ncbi.nlm.nih.gov/pubmed/22389472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-0980 |
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