Platelets of pseudohypoparathyroid patients: Evidence that distinct receptor-cyclase coupling proteins mediate stimulation and inhibition of adenylate cyclase

We studied platelets of patients with the genetic disorder pseudohypoparathyroidism (PHP) to test whether the nucleotide-binding proteins mediating stimulation of adenylate cyclase (termed N(s)) are identical to those mediating inhibition of cyclase (termed N(i)). Functional responses to hormones th...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Motulsky, Harvey J., Hughes, Richard J., Brickman, Arnold S., Farfel, Zvi, Bourne, Henry R., Insel, Paul A.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1982
Sujets:	Biological Sciences: Medical Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346604/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6287473/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.13.4193
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