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Platelets of pseudohypoparathyroid patients: Evidence that distinct receptor-cyclase coupling proteins mediate stimulation and inhibition of adenylate cyclase

We studied platelets of patients with the genetic disorder pseudohypoparathyroidism (PHP) to test whether the nucleotide-binding proteins mediating stimulation of adenylate cyclase (termed N(s)) are identical to those mediating inhibition of cyclase (termed N(i)). Functional responses to hormones th...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Motulsky, Harvey J., Hughes, Richard J., Brickman, Arnold S., Farfel, Zvi, Bourne, Henry R., Insel, Paul A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1982
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346604/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6287473/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.13.4193
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