Hyperosmolarity-induced lipid droplet formation depends on ceramide production by neutral sphingomyelinase 2

Hyperosmolarity (HO) imposes a remarkable stress on membranes, especially in tissues in direct contact with the external environment. Our efforts were focused on revealing stress-induced lipid changes that precede the inflammatory cytokine response in human corneal epithelial cells exposed to increa...

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Bibliographic Details
Main Authors: Robciuc, Alexandra, Hyötyläinen, Tuulia, Jauhiainen, Matti, Holopainen, Juha M.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2012
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465998/
https://ncbi.nlm.nih.gov/pubmed/22899568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M026732
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