De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells.

We have investigated the block to expression of Moloney murine leukemia virus in murine embryonal carcinoma (EC) cells. Infected EC cells were found to contain up to 100 integrated proviral genomes. However, expression of virus as measured by XC plaque and virus-specific RNA synthesis did not occur...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Stewart, C L, Stuhlmann, H, Jähner, D, Jaenisch, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1982
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346584/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6955793/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.13.4098
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