De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells.
We have investigated the block to expression of Moloney murine leukemia virus in murine embryonal carcinoma (EC) cells. Infected EC cells were found to contain up to 100 integrated proviral genomes. However, expression of virus as measured by XC plaque and virus-specific RNA synthesis did not occur...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1982
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346584/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6955793/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.13.4098 |
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