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Mitochondrial dysfunction and activation of iNOS are responsible for the palmitate-induced decrease in adiponectin synthesis in 3T3L1 adipocytes

Mitochondrial dysfunction and endoplasmic reticulum (ER) stress are considered the key determinants of insulin resistance. Impaired mitochondrial function in obese animals was shown to induce the ER stress response, resulting in reduced adiponectin synthesis in adipocytes. The expression of inducibl...

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Détails bibliographiques
Auteurs principaux: Jeon, Min Jae, Leem, Jaechan, Ko, Myoung Seok, Jang, Jung Eun, Park, Hye-Sun, Kim, Hyun Sik, Kim, Mina, Kim, Eun Hee, Yoo, Hyun Ju, Lee, Chul-Ho, Park, In-Sun, Lee, Ki-Up, Koh, Eun Hee
Format: Artigo
Langue:Inglês
Publié: Korean Society for Biochemistry and Molecular Biology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465750/
https://ncbi.nlm.nih.gov/pubmed/22809900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2012.44.9.064
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