Mitochondrial dysfunction and activation of iNOS are responsible for the palmitate-induced decrease in adiponectin synthesis in 3T3L1 adipocytes

Mitochondrial dysfunction and endoplasmic reticulum (ER) stress are considered the key determinants of insulin resistance. Impaired mitochondrial function in obese animals was shown to induce the ER stress response, resulting in reduced adiponectin synthesis in adipocytes. The expression of inducibl...

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Autori principali: Jeon, Min Jae, Leem, Jaechan, Ko, Myoung Seok, Jang, Jung Eun, Park, Hye-Sun, Kim, Hyun Sik, Kim, Mina, Kim, Eun Hee, Yoo, Hyun Ju, Lee, Chul-Ho, Park, In-Sun, Lee, Ki-Up, Koh, Eun Hee
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Society for Biochemistry and Molecular Biology 2012
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465750/
https://ncbi.nlm.nih.gov/pubmed/22809900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2012.44.9.064
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