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Polycomb repressive complex 1 activities determine the columnar organization of motor neurons

Polycomb repressive complexes (PRCs) establish and maintain gene repression through chromatin modifications, but their specific roles in cell fate determination events are poorly understood. Here we show an essential role for the PRC1 component Bmi1 in motor neuron (MN) subtype differentiation throu...

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Detalles Bibliográficos
Main Authors: Golden, Molly G., Dasen, Jeremy S.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465743/
https://ncbi.nlm.nih.gov/pubmed/23028147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.199133.112
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