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Polycomb repressive complex 1 activities determine the columnar organization of motor neurons

Polycomb repressive complexes (PRCs) establish and maintain gene repression through chromatin modifications, but their specific roles in cell fate determination events are poorly understood. Here we show an essential role for the PRC1 component Bmi1 in motor neuron (MN) subtype differentiation throu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Golden, Molly G., Dasen, Jeremy S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465743/
https://ncbi.nlm.nih.gov/pubmed/23028147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.199133.112
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