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Polycomb repressive complex 1 activities determine the columnar organization of motor neurons
Polycomb repressive complexes (PRCs) establish and maintain gene repression through chromatin modifications, but their specific roles in cell fate determination events are poorly understood. Here we show an essential role for the PRC1 component Bmi1 in motor neuron (MN) subtype differentiation throu...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465743/ https://ncbi.nlm.nih.gov/pubmed/23028147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.199133.112 |
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