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Ube3a-ATS is an atypical RNA polymerase II transcript that represses the paternal expression of Ube3a

The Angelman syndrome gene, UBE3A, is subject to genomic imprinting controlled by mechanisms that are only partially understood. Its antisense transcript, UBE3A-ATS, is also imprinted and hypothesized to suppress UBE3A in cis. In this research, we showed that the mouse antisense ortholog, Ube3a-ATS,...

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Detalhes bibliográficos
Main Authors: Meng, Linyan, Person, Richard E., Beaudet, Arthur L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465693/
https://ncbi.nlm.nih.gov/pubmed/22493002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds130
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