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Ube3a-ATS is an atypical RNA polymerase II transcript that represses the paternal expression of Ube3a
The Angelman syndrome gene, UBE3A, is subject to genomic imprinting controlled by mechanisms that are only partially understood. Its antisense transcript, UBE3A-ATS, is also imprinted and hypothesized to suppress UBE3A in cis. In this research, we showed that the mouse antisense ortholog, Ube3a-ATS,...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465693/ https://ncbi.nlm.nih.gov/pubmed/22493002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds130 |
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