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Ube3a-ATS is an atypical RNA polymerase II transcript that represses the paternal expression of Ube3a

The Angelman syndrome gene, UBE3A, is subject to genomic imprinting controlled by mechanisms that are only partially understood. Its antisense transcript, UBE3A-ATS, is also imprinted and hypothesized to suppress UBE3A in cis. In this research, we showed that the mouse antisense ortholog, Ube3a-ATS,...

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Bibliografiske detaljer
Main Authors: Meng, Linyan, Person, Richard E., Beaudet, Arthur L.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465693/
https://ncbi.nlm.nih.gov/pubmed/22493002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds130
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