UV-induced inhibition of transcription involves repression of transcription initiation and phosphorylation of RNA polymerase II

Cells from patients with Cockayne syndrome (CS) are hypersensitive to DNA-damaging agents and are unable to restore damage-inhibited RNA synthesis. On the basis of repair kinetics of different types of lesions in transcriptionally active genes, we hypothesized previously that impaired transcription...

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Detalhes bibliográficos
Main Authors: Rockx, Davy A. P., Mason, Rebecca, van Hoffen, Anneke, Barton, Michelle Craig, Citterio, Elisabetta, Bregman, David B., van Zeeland, Albert A., Vrieling, Harry, Mullenders, Leon H. F.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC27054/
https://ncbi.nlm.nih.gov/pubmed/10973477
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