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UV-induced inhibition of transcription involves repression of transcription initiation and phosphorylation of RNA polymerase II

Cells from patients with Cockayne syndrome (CS) are hypersensitive to DNA-damaging agents and are unable to restore damage-inhibited RNA synthesis. On the basis of repair kinetics of different types of lesions in transcriptionally active genes, we hypothesized previously that impaired transcription...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Rockx, Davy A. P., Mason, Rebecca, van Hoffen, Anneke, Barton, Michelle Craig, Citterio, Elisabetta, Bregman, David B., van Zeeland, Albert A., Vrieling, Harry, Mullenders, Leon H. F.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27054/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10973477/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.180169797
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