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Protein Thioester Synthesis Enabled by Sortase
Proteins containing a C-terminal thioester are important intermediates in semi-synthesis. Currently there is one main method for the synthesis of protein thioesters that relies upon the use of engineered inteins. Here we report a simple strategy, utilizing Sortase A, for routine preparation of recom...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465687/ https://ncbi.nlm.nih.gov/pubmed/22686546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja302354v |
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