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Alpha-fetoprotein -Thymidine Kinase-Luciferase Knockin Mice: A Novel Model for Dual Modality Longitudinal Imaging of Tumorigenesis in Liver

BACKGROUND AND AIMS: Hepatocellular carcinoma (HCC) is frequently a lethal disease and one of the few malignancies that are still increasing in incidences around the world. Better animal models are highly desired to investigate the molecular basis of HCC and to develop novel therapeutic strategies....

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Autors principals: Lu, Xincheng, Guo, Hong, Molter, Joseph, Miao, Hui, Gerber, Lizabeth, Hu, Yiduo, Barnes, Ellen L., Vogel, Hannes, Lee, Zhenghong, Luo, Guangbin, Wang, Bingcheng
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465678/
https://ncbi.nlm.nih.gov/pubmed/21354236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2010.10.020
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