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Alpha-fetoprotein -Thymidine Kinase-Luciferase Knockin Mice: A Novel Model for Dual Modality Longitudinal Imaging of Tumorigenesis in Liver

BACKGROUND AND AIMS: Hepatocellular carcinoma (HCC) is frequently a lethal disease and one of the few malignancies that are still increasing in incidences around the world. Better animal models are highly desired to investigate the molecular basis of HCC and to develop novel therapeutic strategies....

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Detalhes bibliográficos
Main Authors: Lu, Xincheng, Guo, Hong, Molter, Joseph, Miao, Hui, Gerber, Lizabeth, Hu, Yiduo, Barnes, Ellen L., Vogel, Hannes, Lee, Zhenghong, Luo, Guangbin, Wang, Bingcheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465678/
https://ncbi.nlm.nih.gov/pubmed/21354236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2010.10.020
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