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Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo
We present the first large-scale identification of lariats—the transient branched introns that are released as a byproduct of pre-mRNA splicing. The locations of the branchpoints in these introns provide insight into the early steps of splicing. From this data set, we have developed a comprehensive...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465671/ https://ncbi.nlm.nih.gov/pubmed/22705790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2327 |
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