Mixed antagonistic effects of the ginkgolides at recombinant human ρ(1) GABA(C) receptors

The diterpene lactones of Ginkgo biloba, ginkgolides A, B and C are antagonists at a range of Cys-loop receptors. This study examined the effects of the ginkgolides at recombinant human ρ(1) GABA(C) receptors expressed in Xenopus oocytes using two-electrode voltage clamp. The ginkgolides were modera...

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Hlavní autoři: Huang, Shelley H., Lewis, Trevor M., Lummis, Sarah C.R., Thompson, Andrew J., Chebib, Mary, Johnston, Graham A.R., Duke, Rujee K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Pergamon Press 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465557/
https://ncbi.nlm.nih.gov/pubmed/22828636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.06.067
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