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Bioluminescence Assay Platform for Selective and Sensitive Detection of Ub/Ubl Proteases
As the importance of ubiquitylation in certain disease states becomes increasingly apparent, the enzymes responsible for removal of ubiquitin (Ub) from target proteins, deubiquitylases (DUBs), are becoming attractive targets for drug discovery. For rapid identification of compounds that alter DUB fu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465522/ https://ncbi.nlm.nih.gov/pubmed/22705352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2012.06.004 |
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