Synthesis and Biological Evaluation of Two Agents for Imaging Estrogen Receptor β by Positron Emission Tomography: Challenges in PET Imaging of a Low Abundance Target

INTRODUCTION: Independent measurement of the levels of both the estrogen receptors, ERα and ERβ, in breast cancer could improve prediction of benefit from endocrine therapies. While ERα levels can be measured by positron emission tomography (PET) using 16α-[(18)F]fluoroestradiol (FES), no effective...

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Detalhes bibliográficos
Main Authors: HakLee, Jae, Peters, Olaf, Lehmann, Lutz, Dence, Carmen S., Sharp, Terry L., Carlson, Kathryn E., Zhou, Dong, Jeyakumar, M., Welch, Michael J., Katzenellenbogen, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465515/
https://ncbi.nlm.nih.gov/pubmed/22749433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2012.05.011
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