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Paramagnetic Cu(II) For Probing Membrane Protein Structure and Function: Inhibition Mechanism of the Influenza M2 Proton Channel
Paramagnetic Cu(II) ions enhance nuclear spin relaxation in a distance-dependent fashion and can be used as a structural probe of proteins. Cu(II) can also serve as functionally important ligands in proteins. Here we investigate the structural basis of Cu(II) inhibition of the influenza M2 proton ch...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465501/ https://ncbi.nlm.nih.gov/pubmed/22519936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3026328 |
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