Epistasis dominates the genetic architecture of Drosophila quantitative traits

Epistasis—nonlinear genetic interactions between polymorphic loci—is the genetic basis of canalization and speciation, and epistatic interactions can be used to infer genetic networks affecting quantitative traits. However, the role that epistasis plays in the genetic architecture of quantitative tr...

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Hlavní autoři: Huang, Wen, Richards, Stephen, Carbone, Mary Anna, Zhu, Dianhui, Anholt, Robert R. H., Ayroles, Julien F., Duncan, Laura, Jordan, Katherine W., Lawrence, Faye, Magwire, Michael M., Warner, Crystal B., Blankenburg, Kerstin, Han, Yi, Javaid, Mehwish, Jayaseelan, Joy, Jhangiani, Shalini N., Muzny, Donna, Ongeri, Fiona, Perales, Lora, Wu, Yuan-Qing, Zhang, Yiqing, Zou, Xiaoyan, Stone, Eric A., Gibbs, Richard A., Mackay, Trudy F. C.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465439/
https://ncbi.nlm.nih.gov/pubmed/22949659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213423109
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