Epistasis dominates the genetic architecture of Drosophila quantitative traits

Epistasis—nonlinear genetic interactions between polymorphic loci—is the genetic basis of canalization and speciation, and epistatic interactions can be used to infer genetic networks affecting quantitative traits. However, the role that epistasis plays in the genetic architecture of quantitative tr...

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Main Authors: Huang, Wen, Richards, Stephen, Carbone, Mary Anna, Zhu, Dianhui, Anholt, Robert R. H., Ayroles, Julien F., Duncan, Laura, Jordan, Katherine W., Lawrence, Faye, Magwire, Michael M., Warner, Crystal B., Blankenburg, Kerstin, Han, Yi, Javaid, Mehwish, Jayaseelan, Joy, Jhangiani, Shalini N., Muzny, Donna, Ongeri, Fiona, Perales, Lora, Wu, Yuan-Qing, Zhang, Yiqing, Zou, Xiaoyan, Stone, Eric A., Gibbs, Richard A., Mackay, Trudy F. C.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2012
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465439/
https://ncbi.nlm.nih.gov/pubmed/22949659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213423109
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