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Epistasis and Quantitative Traits: Using Model Organisms to Study Gene-Gene Interactions
The role of epistasis in the genetic architecture of quantitative traits is controversial, despite the biological plausibility that non-linear molecular interactions underpin the genotype-phenotype map. This controversy arises because most genetic variation for quantitative traits is additive. Howev...
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Format: | Artigo |
Language: | Inglês |
Published: |
2013
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Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3918431/ https://ncbi.nlm.nih.gov/pubmed/24296533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3627 |
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