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Single-cell analysis of early B-lymphocyte development suggests independent regulation of lineage specification and commitment in vivo

To better understand the process of B-lymphocyte lineage restriction, we have investigated molecular and functional properties in early B-lineage cells from Pax-5–deficient animals crossed to a B-lineage–restricted reporter mouse, allowing us to identify B-lineage–specified progenitors independently...

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Detalhes bibliográficos
Main Authors: Zandi, Sasan, Åhsberg, Josefine, Tsapogas, Panagiotis, Stjernberg, Jenny, Qian, Hong, Sigvardsson, Mikael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465423/
https://ncbi.nlm.nih.gov/pubmed/23019372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210144109
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