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Single-cell analysis of early B-lymphocyte development suggests independent regulation of lineage specification and commitment in vivo
To better understand the process of B-lymphocyte lineage restriction, we have investigated molecular and functional properties in early B-lineage cells from Pax-5–deficient animals crossed to a B-lineage–restricted reporter mouse, allowing us to identify B-lineage–specified progenitors independently...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465423/ https://ncbi.nlm.nih.gov/pubmed/23019372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210144109 |
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