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E2A transcription factors limit expression of Gata3 to facilitate T lymphocyte lineage commitment
The E2A transcription factors promote the development of thymus-seeding cells, but it remains unknown whether these proteins play a role in T lymphocyte lineage specification or commitment. Here, we showed that E2A proteins were required to promote T-lymphocyte commitment from DN2 thymocytes and to...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3587319/ https://ncbi.nlm.nih.gov/pubmed/23297135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-08-449447 |
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