Reversible cycling between cysteine persulfide-ligated [2Fe-2S] and cysteine-ligated [4Fe-4S] clusters in the FNR regulatory protein

Fumarate and nitrate reduction (FNR) regulatory proteins are O(2)-sensing bacterial transcription factors that control the switch between aerobic and anaerobic metabolism. Under anaerobic conditions [4Fe-4S](2+)-FNR exists as a DNA-binding homodimer. In response to elevated oxygen levels, the [4Fe-4...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhang, Bo, Crack, Jason C., Subramanian, Sowmya, Green, Jeffrey, Thomson, Andrew J., Le Brun, Nick E., Johnson, Michael K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2012
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465412/
https://ncbi.nlm.nih.gov/pubmed/23019358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208787109
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