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Superoxide-mediated amplification of the oxygen-induced switch from [4Fe-4S] to [2Fe-2S] clusters in the transcriptional regulator FNR

In Escherichia coli, the switch between aerobic and anaerobic metabolism is controlled primarily by FNR (regulator of fumarate and nitrate reduction), the protein that regulates the transcription of >100 genes in response to oxygen. Under oxygen-limiting conditions, FNR binds a [4Fe-4S](2+) clust...

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Detalhes bibliográficos
Main Authors: Crack, Jason C., Green, Jeffrey, Cheesman, Myles R., Le Brun, Nick E., Thomson, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892919/
https://ncbi.nlm.nih.gov/pubmed/17267605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609514104
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