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Kinetics and mechanism of DNA uptake into the cell nucleus

Gene transfer to eukaryotic cells requires the uptake of exogenous DNA into the cell nucleus. Except during mitosis, molecular access to the nuclear interior is limited to passage through the nuclear pores. Here we demonstrate the nuclear uptake of extended linear DNA molecules by a combination of f...

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Detalhes bibliográficos
Main Authors: Salman, H., Zbaida, D., Rabin, Y., Chatenay, D., Elbaum, M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC34654/
https://ncbi.nlm.nih.gov/pubmed/11390964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.121067698
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