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Kinetics and mechanism of DNA uptake into the cell nucleus

Gene transfer to eukaryotic cells requires the uptake of exogenous DNA into the cell nucleus. Except during mitosis, molecular access to the nuclear interior is limited to passage through the nuclear pores. Here we demonstrate the nuclear uptake of extended linear DNA molecules by a combination of f...

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Detalles Bibliográficos
Autores principales: Salman, H., Zbaida, D., Rabin, Y., Chatenay, D., Elbaum, M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC34654/
https://ncbi.nlm.nih.gov/pubmed/11390964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.121067698
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