Chromatin conformation governs T-cell receptor Jβ gene segment usage

T cells play fundamental roles in adaptive immunity, relying on a diverse repertoire of T-cell receptor (TCR) α and β chains. Diversity of the TCR β chain is generated in part by a random yet intrinsically biased combinatorial rearrangement of variable (Vβ), diversity (Dβ), and joining (Jβ) gene seg...

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Detalles Bibliográficos
Main Authors: Ndifon, Wilfred, Gal, Hilah, Shifrut, Eric, Aharoni, Rina, Yissachar, Nissan, Waysbort, Nir, Reich-Zeliger, Shlomit, Arnon, Ruth, Friedman, Nir
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465372/
https://ncbi.nlm.nih.gov/pubmed/22984176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203916109
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