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Chromatin conformation governs T-cell receptor Jβ gene segment usage
T cells play fundamental roles in adaptive immunity, relying on a diverse repertoire of T-cell receptor (TCR) α and β chains. Diversity of the TCR β chain is generated in part by a random yet intrinsically biased combinatorial rearrangement of variable (Vβ), diversity (Dβ), and joining (Jβ) gene seg...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465372/ https://ncbi.nlm.nih.gov/pubmed/22984176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203916109 |
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